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Priapism is a rare side effect that happens when you have a single erection that lasts 4 hours or more. This can be dangerous because blood can pool in the penis and lose oxygen, making your erection painful and damaging tissue. Always consult a healthcare provider before using Levitra to ensure it’s safe based on your medical history and current medications. If your health changes or if you’re prescribed a new medication, it’s a good idea to let your prescriber know as soon as possible. This is because certain conditions and medications can interact with Levitra.
Like most medications, you should store Levitra in a cool, dry environment. You don't want to expose Levitra to direct sunlight or humidity. Some great locations you can store Levitra are kitchen cabinets or medicine drawers. It takes around an hour to work and should only be taken once daily. Once Levitra enters the bloodstream, with proper stimulation, it can help with penetrative sex. Levitra contains the active ingredient vardenafil, which is also its generic version.

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The cGMP is primarily responsible for buy xanax without prescrition increasing and decreasing the size of the blood vessels carrying blood to and from the penis. A rare vision problem called NAION -- short for "nonarteritic anterior ischemic optic neuropathy" -- has been reported by a few men using these drugs. Always follow the directions on your prescription label carefully. Also, make sure to ask your doctor or pharmacist to explain anything you don’t understand. Other vardenafil interactions include antidepressants, antibiotics, antifungals, medications for a prostate disorder and HIV/AIDS medicine.

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A suitable time interval following dosing of LEVITRA for the safe administration of nitrates or nitric oxide donors has not been determined. Inform patients that LEVITRA is contraindicated with regular and/or intermittent use of organic nitrates. There have been rare reports of prolonged erections greater than 4 hours and priapism (painful erections greater than 6 hours in duration) for this class of compounds, including vardenafil.

Patients prescribed LEVITRA who are taking alpha-blockers should be started on the lowest recommended starting dose of LEVITRA (see Drug Interactiona and DOSAGE AND ADMINISTRATION). Patients should be advised of the possible occurrence of symptoms related to postural hypotension and appropriate countermeasures. Patients should be advised to contact the prescribing physician if other anti-hypertensive drugs or new medications that may interact with LEVITRA are prescribed by another healthcare provider. The pharmacokinetics of vardenafil are approximately dose proportional over the recommended dose range. Vardenafil is eliminated predominantly by hepatic metabolism, mainly by CYP3A4 and to a minor extent, CYP2C isoforms.